Welcome to Ben Greenfield’s Weekly Roundup!
In this weekly post, I share with you my most interesting discoveries of the week, including the latest news on the fronts of fitness, nutrition, health, wellness, biohacking, and anti-aging research. I also recap my upcoming events and special announcements so you can keep up with opportunities to learn, giveaways, discounts, and more!
New Discoveries
My *Exact* Sleep Routine Revealed + How I CONSISTENTLY Achieve a 96+% Sleep Score 🌙 🛌
If you want better sleep, you’ll need to stop looking for one magic supplement, gadget, or trick…
That’s because great sleep comes from building the right system before your head hits the pillow.
In my latest YouTube video, I walk you through the four top variables of getting great sleep every night: temperature, light, stress, and sound. You’ll also discover the exact tools, tactics, and travel hacks I use to keep my sleep score high (even when I’m out of my normal environment).
You’ll see how I cool my bedroom, manage blue light, use red light at night, downshift my nervous system, keep EMFs low, leverage breathwork, supplements, and sound strategically, and yes… tape my mouth and nose before bed.
If you’ve been waking up groggy no matter how many hours of sleep you get or feel like you can’t take another night of insomnia, you can check out the video below or watch it here.
Creatine Is “Bad For Your Kidneys”?! A Review of 684 Randomized Controlled Trials Just Said Otherwise… 💪🧠
Despite being one of the most studied supplements in history, creatine still gets hit with the same questions: Does it hurt your kidneys? Is it safe long-term? Are there hidden side effects nobody is talking about?
A new review of 684 randomized controlled trials involving more than 12,800 participants provides a pretty clear answer: not really.
In fact, researchers have found creatine’s side effects to be virtually nonexistent.
If anything, a small number of people experienced mild gastrointestinal discomfort, but that was about it. There was no consistent evidence that higher doses or longer-term supplementation increased the risk of kidney, liver, musculoskeletal, gastrointestinal, or other health problems. In many cases, placebo groups reported similar rates of side effects.
The kidney concern is especially worth addressing because it’s one of the biggest myths surrounding creatine. The notion that “creatine is bad for your kidneys” largely comes from the fact that creatine can raise serum creatinine, a marker commonly used to estimate kidney function. Some physicians see elevated creatinine levels and become concerned.
But a separate 2026 systematic review and meta-analysis found that while creatine supplementation does increase serum creatinine, it doesn’t significantly alter other key markers of kidney health, including urea levels and estimated glomerular filtration rate (eGFR). In other words, the lab number changes, but there is no evidence that the kidneys themselves are being harmed.
So what does this tell you? Creatine continues to be one of the safest, most effective, and most evidence-backed supplements available for strength, muscle mass, recovery, cognitive performance, healthy aging, and even resilience during sleep deprivation.
Personally, I use plain old creatine monohydrate, although I make sure it’s exceptionally pure (I use Kion Creatine, which contains nothing but high-quality creatine monohydrate with rigorous purity testing).
Want to dive deeper into how creatine impacts muscle growth, brain function, performance, recovery, and longevity? You can check out the resources below:
Should I Create A Boundless Audiobook? I Need Your Input 🎧
You may already know about my book, Boundless: Upgrade Your Brain, Optimize Your Body & Defy Aging.
What started as a book somehow turned into a massive health, performance, and longevity encyclopedia.
The fully updated and revised edition came out recently, but let’s be honest: it’s a big book, and I know that can be intimidating. For many people, finding the time to sit down and read hundreds of pages isn’t easy.
That’s why I’m considering creating a full audiobook version, so you can absorb the material while driving, walking, training, traveling, or doing just about anything else.
Before I make the investment to produce it, I’d love your feedback.
If you’d be interested in listening to Boundless on Audible or another audiobook platform, please take a few seconds to let me know. Your input will directly influence whether this project moves forward.
You can share your opinion here (the poll will be open from June 4 to 17).
Thanks for helping me decide!
This Week in Health & Performance: What the Latest Research Says
🏥💊 Oral GLP-1s Are Coming Fast: Injectable GLP-1 drugs may soon have serious competition. New research on orforglipron, an oral GLP-1 receptor agonist, shows promising results for weight loss and metabolic health without the need for injections. If future studies continue to support its effectiveness and safety, this could dramatically expand access to GLP-1 therapy and become one of the biggest pharmaceutical categories of the decade, and a real cash cow (read the study here).
🦵⚡ A Simple Exercise For Stubborn Knee Pain: New research continues to support eccentric single-leg squats on a slant board as an effective strategy for reducing knee pain and improving function. If the full range of motion isn’t comfortable, partial reps can still provide benefits while gradually building strength and resilience around the joint (full study here).
🏃♂️🩸 Ultrarunning May Accelerate Red Blood Cell Aging: While ultrarunning can build tremendous mental toughness and endurance, new research suggests it may also come with physiological tradeoffs. Researchers found evidence of accelerated red blood cell aging and increased red blood cell breakdown after both 40 km and 171 km races, likely driven by inflammation, oxidative stress, altered kynurenine metabolism, and disruptions in copper balance. The findings don’t mean ultrarunning is “bad,” but they do add to the growing body of evidence that more exercise isn’t always better when it comes to long-term health and recovery (read more). For more on why long, slow endurance training may not be the best way to stay fit, listen to my recent podcasts with Mark Sisson here and here.
Key Takeaway: This week’s research highlights an important theme: the most effective health strategies often balance performance with sustainability. Whether it’s next-generation GLP-1 therapies, smarter approaches to knee rehabilitation, or understanding the physiological costs of extreme endurance exercise, optimizing health requires doing the right things at the right dose.
Want to dive deeper? Click the links above to explore the research, and click here to follow me on X for all the latest health and performance news hot off the press!
Product Of The Week
::: Recover Smarter & Save Up to $2,100 on Sunlighten Saunas 🔥🧖 :::
Most people focus on training harder, yet the real key is recovering better.
Resilience is your body’s ability to adapt to stress, recover efficiently, and come back stronger. When recovery improves, so do your performance, energy levels, and capacity to handle whatever life throws your way.
That’s one reason I consistently use infrared sauna therapy. Regular sauna sessions can support circulation, muscle recovery, healthy stress responses, and overall recovery, helping your body perform more consistently over time.
Not all infrared saunas are built the same, though. The infrared sauna I use at home is the Sunlighten mPulse, which implements something called PulseIQ™ technology to deliver red light plus near-, mid-, and far-infrared wavelengths separately rather than blended into a single output.
That precision matters because each wavelength targets different tissue depths and biological processes, and your body can actually absorb more of it.
If you want to improve how your body handles stress and recovers from it, Sunlighten’s saunas are worth a closer look (they are also low-EMF, which is super important in terms of your electrical environment!).
You can use code BEN here to save up to $2,100 plus get FREE shipping for a limited time.
Podcasts I Recorded This Week:

Latest Seed Oil Controversy, Most Important Body Part?, CBN For Sleep & More! Solosode #501

The Latest Content I Was Featured On This Week:
My Article Feed:
My full article feed and all archives of my articles are here.
This Week’s Most Popular Instagram Post:
This Week’s Most Popular Tweet:
This Week’s Most Popular Facebook Post:
Cheers,
Ben




